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ACTN2 抗体

This anti-ACTN2 antibody is a 兔 单克隆 antibody detecting ACTN2 in WB 和 IF. Suitable for 人.
产品编号 ABIN7265397
发货至: 中国

Quick Overview for ACTN2 抗体 (ABIN7265397)

抗原

See all ACTN2 抗体
ACTN2 (Actinin, alpha 2 (ACTN2))

适用

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宿主

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克隆类型

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单克隆

标记

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This ACTN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    ACTN2 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human ACTN2

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ACTN2 (Actinin, alpha 2 (ACTN2))

    别名

    ACTN2

    背景

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],CMD1AA, CMH23,Apoptosis,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microfilaments,Heart,Heart_Cardiac arrhythmias,Heart_Contractility,Immunology & Inflammation,Signal Transduction,T Cell Receptor Signaling Pathway,ACTN2

    分子量

    103kDa

    基因ID

    88

    UniProt

    P35609

    途径

    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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